Precautions While on this Medicine
You should not use Actiq unless you are already being treated with a similar opioid pain
medicine and your body is tolerant to it. Opioid medicines include fentanyl (Actiq,
Duragesic), hydrocodone (Lortab, Vicodin), hydromorphone (Dilaudid, Palladone), morphine
(Kadian, MS Contin, Oramorph, and others), oxycodone (Oxycontin), oxymorphone (Numorphan,
Opana), and others. Talk with your doctor if you are not sure you are opioid-tolerant.
Do not use Actiq if you have used an MAO inhibitor such as:
- isocarboxazid (Marplan)
- phenelzine (Nardil)
- rasagiline (Azilect)
- selegiline (Eldepryl, Emsam)
- tranylcypromine (Parnate)
within the past 14 days. SERIOUS, life-threatening side effects can occur if you use
fentanyl before the MAO inhibitor has cleared from your body.
You should not use this medication if you have had an allergic reaction or severe side
effects when using any narcotic pain medicine.
Before using Actiq, tell your doctor if you are allergic to any drugs, or if you have:
- a breathing disorder such as asthma or chronic obstructive pulmonary disease (COPD)
- a seizure disorder
- a history of head injury or brain tumor
- liver or kidney disease
- low blood pressure, heart disease
- a history of depression or other mental illness
- a history of drug or alcohol addiction
If you have any of these conditions, you may not be able to use this medication, or you
may need a dosage adjustment or special tests during treatment.
FDA pregnancy category C. It is not known whether Actiq is harmful to an unborn baby. It
could cause addiction or withdrawal symptoms in newborn if the mother uses fentanyl
citrate during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant
during treatment. Tell your doctor if you are pregnant or plan to become pregnant during
treatment. This medication can pass into breast milk and may cause sleepiness or breathing
problems in a nursing baby. Actiq may also cause addiction and withdrawal symptoms in a
nursing infant. Do not use this medication without telling your doctor if you are
breast-feeding a baby. Older adults may be more sensitive to the effects of this medicine.
If you are diabetic, you should know that each Actiq lozenge contains 2 grams (one-half
teaspoon) of sugar.