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Generic Name:
lorazepam (lor-A-ze-pam)
Brand Names:
Ativan®
Classification:
Benzodiazepine
Issue Date:
1989
Ativan is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Ativan
affects chemicals in the brain that may become unbalanced and cause anxiety. Ativan
is used to treat anxiety disorders. Ativan may also be used for purposes other than
those listed here.
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Before Using This Medicine
Do not use this medication if you are allergic to Ativan or to other benzodiazepines such
as:
- alprazolam (Xanax®)
- chlordiazepoxide (Librium®)
- clorazepate (Tranxene®)
- diazepam (Valium®)
- oxazepam (Serax®)
This medication can cause birth defects in an unborn baby. Do not use Ativan if you are
pregnant.
Before taking Ativan, tell your doctor if you have:
- any breathing problems
- glaucoma
- kidney or liver disease
- a history of depression, suicidal thoughts
- or addiction to drugs or alcohol
Do not drink alcohol while taking Ativan. This medication can increase the effects of
alcohol.
Avoid using other medicines that make you sleepy. They can add to sleepiness caused by Ativan.
Ativan may be habit-forming and should be used only by the person it was prescribed for.
Ativan should never be shared with another person, especially someone who has a history
of drug abuse or addiction. Keep the medication in a secure place where others cannot get to
it.
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How To Use This Medicine
Take this medication exactly as it was prescribed for you. Do not take the medication in
larger amounts, or take it for longer than recommended by your doctor. Follow the
directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this
medication.
Measure the liquid form of Ativan with a special dose-measuring spoon or cup, not a regular
table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Ativan should be used for only a short time. Do not take this medication for longer than 4
months without your doctor's advice.
Ativan may be habit-forming and should be used only by the person it was prescribed for.
Ativan should never be shared with another person, especially someone who has a history
of drug abuse or addiction. Keep the medication in a secure place where others cannot get to
it.
Contact your doctor if this medicine seems to stop working as well in treating your symptoms.
Do not stop using Ativan suddenly without first talking to your doctor. You may need to
use less and less before you stop the medication completely.
Your symptoms may return when you stop using Ativan after using it over a long period of
time. You may also have seizures or withdrawal symptoms when you stop using Ativan.
Withdrawal symptoms may include:
- tremor
- sweating
- muscle cramps
- stomach pain
- vomiting
- unusual thoughts or behavior
- seizure (convulsions)
To be sure this medication is not causing harmful effects, your doctor may need to check your
progress on a regular basis. Do not miss any scheduled visits to your doctor.
Store Ativan at room temperature away from moisture, heat, and light.
Keep track of how many pills have been used from each new bottle of this medicine.
Benzodiazepines are drugs of abuse and you should be aware if any person in the household is
using this medicine improperly or without a prescription.
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Precautions While on this Medicine
Before taking Ativan, tell your doctor if you are allergic to any drugs, or if you have:
- narrow-angle glaucoma
- asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD)
- history of depression or suicidal thoughts or behavior
- history of drug or alcohol addiction
- allergic to Ativan or to other benzodiazepines, such as:
- alprazolam (Xanax®)
- chlordiazepoxide (Librium®)
- clorazepate (Tranxene®)
- diazepam (Valium®)
- oxazepam (Serax®)
If you have any of these conditions, you may not be able to use Ativan, or you may need a
dosage adjustment or special tests during treatment.
Ativan can cause birth defects in an unborn baby. Do not use Ativan without your doctor's
consent if you are pregnant. Tell your doctor if you become pregnant during treatment.
Use an effective form of birth control while you are using this medication.
It is not known whether Ativan passes into breast milk or if it could harm a nursing baby. Do
not use this medication without telling your doctor if you are breast-feeding a baby.
The sedative effects of Ativan may last longer in older adults. Accidental falls are common
in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental
injury while you are taking Ativan.
Do not give this medication to a child younger than 12 years old.
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If You Miss A Dose
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip
the missed dose and take the medicine at your next regularly scheduled time. Do not
take extra medicine to make up the missed dose.
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Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction:
- skin rash or hives
- difficulty breathing
- swelling of your face, lips, tongue, or throat
Call your doctor at once if you have any of these serious side effects:
- confusion, depressed mood, thoughts of suicide or hurting yourself
- hyperactivity, agitation, hostility
- hallucinations
- feeling light-headed, fainting
Less serious side effects are more likely to occur, such as:
- drowsiness, dizziness, tiredness
- blurred vision
- sleep problems (insomnia)
- muscle weakness, lack of balance or coordination
- amnesia or forgetfulness, trouble concentrating
- nausea, vomiting, constipation
- appetite changes
- skin rash
Side effects other than those listed here may also occur. Talk to your doctor about
any side effect that seems unusual or that is especially bothersome.
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Drug Interactions
Before taking Ativan, tell your doctor if you are using any of the following drugs:
- amobarbital (Amytal®)
- butabarbital (Butisol®)
- mephobarbital (Mebaral®)
- secobarbital (Seconal®)
- phenobarbital (Luminal®, Solfoton®)
- isocarboxazid (Marplan®)
- phenelzine (Nardil®)
- rasagiline (Azilect®)
- selegiline (Eldepryl®, Emsam®)
- tranylcypromine (Parnate®)
- chlorpromazine (Thorazine®)
- haloperidol (Haldol®)
- mesoridazine (Serentil®)
- pimozide (Orap®)
- thioridazine (Mellaril®)
- butorphanol (Stadol®)
- codeine
- hydrocodone (Loratab®, Vicodin®)
- levorphanol (Levo-Dromoran®)
- meperidine (Demerol®)
- methadone (Dolophine®, Methadose®)
- morphine (Kadian®, MS Contin®, Oramorph®)
- naloxone (Narcan®)
- oxycodone (OxyContin®)
- propoxyphene (Darvon®, Darvocet®)
- amitriptyline (Elavil®, Etrafon®)
- amoxapine (Ascendin®)
- citalopram (Celexa®)
- clomipramine (Anafranil®)
- desipramine (Norpramin®)
- doxepin (Sinequan®)
- escitalopram (Lexapro®)
- fluoxetine (Prozac®, Sarafem®)
- fluvoxamine (Luvox®)
- imipramine (Janimine®, Tofranil®)
- nortriptyline (Pamelor®)
- paroxetine (Paxil®)
- protriptyline (Vivactil®)
- sertraline (Zoloft®)
- trimipramine (Surmontil®)
If you are using any of these drugs, you may not be able to use Ativan, or you may need
dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect Ativan. Tell your doctor about all the
prescription and over-the-counter medications you use. This includes vitamins, minerals,
herbal products, and drugs prescribed by other doctors. Do not start using a new medication
without telling your doctor.
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