A large number of over-the-counter and prescription medications may interact with Tegretol
in a dangerous way.
Some drugs, such as Biaxin, erythromycin, Darvon or Darvocet DN 100, can make Tegretol
much more toxic, with dangerous blood levels building up surprisingly quickly.
Other anticonvulsants interact with Tegretol in complicated ways and may even reduce
In addition, Tegretol can interfere with the benefits of many other compounds.
Just a few of the many drugs that interact with Tegretol include several different kinds
of antidepressant, the blood thinner Coumadin, the ulcer drug Tagamet, the heart and
blood pressure pills Cardizem CD, Calan SR and Verelan, and certain antibiotics such
as tetracycline, Vibramycin and INH.
Other medications that may cause problems include the asthma drug theophylline,
Haldol, Sandimmune, Danocrine and even flu vaccine and activated charcoal.
It's possible that flavonoids found in the herb echinacea affect the enzyme
(CYP 3A4) responsible for metabolizing many common drugs. If so, medications such as
Tegretol could reach higher levels in the body.
The herb St. Jone's wort might speed elimination of Tegretol from the body, which could
reduce its effectiveness.
Psyllium can affect the absorption of Tgretol; if you take it, it is best to do so at
least an hour after taking Tegretol.
Do not take any other medications or herbs without first checking with your physician
This may not be a complete list of all interactions that may occur. Ask your health
care provider if Sinemet may interact with other medicines that you take. Check with
your health care provider before you start, stop, or change the dose of any medicine.
Talk to your doctor and pharmacist before taking any prescription
or over-the-counter medicines, including herbal products.