Drug Database - Diclofenac
Cataflam®, Voltaren®, Voltaren-XR®
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Diclofenac is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).
Diclofenac works by reducing hormones that cause inflammation and pain in the body.
Diclofenac is used to treat pain or inflammation caused by arthritis, ankylosing
spondylitis, fibromyalgia, chronic fatigue syndrome/myalgic encephalomyelitis.
Before Using This Medicine
This medicine can increase your risk of life-threatening heart or circulation
problems, including heart attack or stroke. This risk will increase the longer you
Do not use this medicine just before or after having heart bypass surgery
(also called coronary artery bypass graft, or CABG).
Seek emergency medical help if you have symptoms of heart or circulation problems, such as:
- chest pain
- shortness of breath
- slurred speech
- problems with vision or balance
Do not use this medication if you are allergic to Diclofenac, or if you have a history
of allergic reaction to aspirin or other NSAIDs.
Before taking Diclofenac, tell your doctor if you are allergic to any drugs, or if you
- a history of heart attack, stroke, or blood clot
- heart disease, congestive heart failure, high blood pressure
- a history of stomach ulcers or bleeding
- liver or kidney disease
- polyps in your nose
- a bleeding or blood clotting disorder
- if you smoke
If you have any of these conditions, you may not be able to use Diclofenac, or you may
need a dosage adjustment or special tests during treatment.
FDA pregnancy category C.
This medication may be harmful to an unborn baby. Tell
your doctor if you are pregnant or plan to become pregnant during treatment.
Taking Diclofenac during the last 3 months of pregnancy may result in birth defects.
Do not take Diclofenac during pregnancy unless your doctor has
told you to. Diclofenac can pass
into breast milk and may harm a nursing baby. Do not use this medication without telling
your doctor if you are breast-feeding a baby. Do not give this medicine to a child without
the advice of a doctor.
How To Use This Medicine
Take this medication exactly as it was prescribed for you. Do not take the medication
in larger amounts, or take it for longer than recommended by your doctor. Follow
the directions on your prescription label.
If you switch brands of Diclofenac, your dose needs may change. Follow your
doctor's instructions about how much medicine to take.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It
is specially made to release medicine slowly in the body. Breaking the pill would cause
too much of the drug to be released at one time.
If you take Diclofenac for a long period of time, your doctor may want to check you on a
regular basis to make sure this medication is not causing harmful effects. Do not miss
any scheduled visits to your doctor.
Precautions While on this Medicine
Do not use any other over-the-counter cold, allergy, or pain medication without first
asking your doctor or pharmacist. Many medicines available over the counter contain aspirin
or other medicines similar to Diclofenac (such as ibuprofen, ketoprofen, or naproxen). If
you take certain products together you may accidentally take too much of this type
of medication. READ THE LABEL of any other medicine you are using to see if it
contains aspirin, ibuprofen, ketoprofen, or naproxen.
Do not drink alcohol while taking Diclofenac. Alcohol can increase the risk of
stomach bleeding caused by Diclofenac. Avoid prolonged exposure to sunlight. Diclofenac
may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear
protective clothing when exposure to the sun is unavoidable.
If You Miss A Dose
Take the missed dose as soon as you remember. If it is almost time for your next dose,
skip the missed dose and take the medicine at your next regularly scheduled time.
not take extra medicine to make up the missed dose.
If You Overdose
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a Diclofenac overdose may include:
- stomach pain
- black or bloody stools
- coughing up blood
- shallow breathing
Get emergency medical help if you have any of these signs of an allergic reaction:
- skin rash or hives
- difficulty breathing
- swelling of your face, lips, tongue, or throat
Call your doctor at once if you have any of these SERIOUS side effects:
- chest pain
- weakness, shortness of breath
- slurred speech
- problems with vision or balance
- black, bloody, or tarry stools
- coughing up blood or vomit that looks like coffee grounds
- swelling or rapid weight gain
- urinating less than usual or not at all
- nausea, stomach pain
- low fever
- loss of appetite
- dark urine, clay-colored stools
- jaundice (yellowing of the skin or eyes)
- sore throat
- headache with a severe blistering, peeling, and red skin rash
- severe tingling, numbness
- pain, muscle weakness
- neck stiffness
- increased sensitivity to light
- purple spots on the skin
- seizure (convulsions)
Less serious side effects are more likely to occur, such as:
- upset stomach, mild heartburn or stomach pain
- diarrhea, constipation
- bloating, gas
- dizziness, headache, nervousness
- skin itching or rash
- blurred vision
- ringing in your ears
This is not a complete list of all side effects that may occur. If you have questions
or need medical advice about side effects, contact your doctor or health care provider.
You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at
Before taking alprazolam, tell your doctor if you are using any of
the following drugs:
- a blood thinner such as warfarin (Coumadin®)
- cyclosporine (Neoral®, Sandimmune®)
- lithium (Eskalith®, Lithobid®)
- methotrexate (Rheumatrex®, Trexall®)
- diuretics (water pills) such as furosemide (Lasix®)
- steroids (prednisone and others)
- aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as:
- etodolac (Lodine®)
- flurbiprofen (Ansaid®)
- indomethacin (Indocin®)
- ketoprofen (Orudis®)
- ketorolac (Toradol®)
- mefenamic acid (Ponstel®)
- meloxicam (Mobic®)
- nabumetone (Relafen)
- naproxen (Aleve®, Naprosyn®)
- piroxicam (Feldene®) and others
- an ACE inhibitor such as:
- benazepril (Lotensin®)
- captopril (Capoten®)
- fosinopril (Monopril®)
- enalapril (Vasotec®)
- lisinopril (Prinivil®, Zestril®)
- ramipril (Altace®), and others
If you are using any of these drugs, you may not be able to use Diclofenac or you
may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect Diclofenac. Tell your doctor
about all the prescription and over-the-counter medications you use. This includes
vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not
start using a new medication without telling your doctor.