Drug Database - Flebogamma
Flebogamma®, Panglobulin NF®
Providing Antibodies Which Fight Infection
Flebogamma may increase the risk of serious and sometimes fatal kidney problems. The risk
may be greater if you already have kidney problems or are older than 65 years of age. You
may also be at increased risk if you have diabetes, dehydration or low blood volume, a
blood infection, or abnormal proteins in the blood (paraproteinemia), or if you are taking
other medicines that may harm the kidney. Contact your doctor immediately if you
experience decreased urination, lower back or flank pain, swelling or bloating, sudden
weight gain, shortness of breath, or weakness.
Providing antibodies to help prevent infection in certain patients who have a weakened
immune system. It may also be used for other conditions as determined by your doctor.
Flebogamma is an immune globulin. It works by providing antibodies which fight infection.
Before Using This Medicine
Do NOT use Flebogamma if:
you are allergic to any ingredient in Flebogamma
you have had a severe allergic reaction (eg, severe rash, hives, difficulty
breathing, dizziness) to sorbitol, thimerosal, blood, or products that are produced
you have had an allergic reaction to gamma globulin or anti-immunoglobulin A (IgA)
you have IgA deficiency or antibodies to IgA
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Flebogamma. Tell your doctor or pharmacist if
you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or
if you have allergies to medicines, foods, or other substances
if you have recently received any vaccinations
if you have heart problems, blood vessel problems (eg, narrowed arteries), thick blood,
or a history of stroke, heart attack, or blood clots
if you have kidney problems, diabetes, dehydration or low blood volume, a blood infection,
abnormal proteins in the blood, or asthma
How to use Flebogamma
Use Flebogamma as directed by your doctor. Check the label on the medicine for exact
Flebogamma is usually administered as an injection at your doctor's office, hospital, or
clinic. If you are using Flebogamma at home, carefully follow the injection procedures
taught to you by your health care provider.
If Flebogamma contains particles or is discolored, or if the vial is cracked or damaged in
any way, do not use it.
Keep this product, as well as syringes and needles, out of the reach of children and away
from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after
use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
Ask your health care provider any questions you may have about how to use Flebogamma.
Safety Information About Flebogamma
Flebogamma may cause lightheadedness. Do not drive, operate machinery, or do anything else
that could be dangerous until you know how you react to Flebogamma. Using Flebogamma
alone, with certain other medicines, or with alcohol may lessen your ability to drive or
perform other potentially dangerous tasks.
Aseptic meningitis syndrome (AMS) has been reported to occur rarely in association with
the use of Flebogamma. This syndrome usually begins within several hours to 2 days
following treatment. Symptoms include severe headache, neck stiffness, drowsiness, fever,
painful eye movements, sensitivity to light, nausea, and vomiting.
Avoid vaccinations with live virus vaccines (eg, measles, mumps, oral polio) while you are
using Flebogamma. Vaccinations may be less effective.
DIABETES PATIENTS: Flebogamma may cause incorrect test results with some blood and
urine glucose tests. Check with your doctor before you adjust the dose of your diabetes
medicine or change your diet.
Some of these products contain latex in the packaging. If you are allergic to latex, ask
your doctor or pharmacist if your product contains latex.
Flebogamma is made from human plasma. There is an extremely low risk of developing a viral
infection or Creutzfeldt-Jakob disease (CJD) after using Flebogamma. Discuss any questions
or concerns with your doctor.
LAB TESTS, including kidney function, blood thickness, and
antibody levels, may be performed to monitor your progress or to check for side effects.
Be sure to keep all doctor and lab appointments.
Use Flebogamma with caution in the
ELDERLY because they may be more sensitive to
its effects, especially kidney failure.
Use Flebogamma with extreme caution in
CHILDREN. Safety and effectiveness of
certain products have not been established for certain age groups. Check with your doctor
or pharmacist if you have questions about the use of Flebogamma in a child.
PREGNANCY and BREAST-FEEDING: It is unknown if Flebogamma can cause harm to the
fetus. If you become pregnant while taking Flebogamma , discuss with your doctor the
benefits and risks of using Flebogamma during pregnancy. It is unknown if Flebogamma is
excreted in breast milk. If you are or will be breast-feeding while you are using
Flebogamma, check with your doctor or pharmacist to discuss the risks to your baby.
Get emergency medical help if you have any of these signs of an allergic reaction:
- Difficulty breathing
- Swelling of your face, lips, tongue, or throat
Seek medical attention right away if any of these SEVERE side effects occur:
- calf pain or tenderness
- chest pain
- dark urine
- decreased urination
- fast or irregular heartbeat
- fever or chills
- lower back or flank pain
- numbness of an arm or a leg
- one-sided weakness
- painful eye movements
- red, swollen, blistered, or peeling skin
- sensitivity to light
- severe headache, dizziness, or stomach pain
- shortness of breath
- speech problems
- stiff neck
- sudden weight gain
- unusual drowsiness
- vision problems
- yellowing of the skin or eyes
Continue taking atomoxetine and talk to your doctor if you have any of these less serious
- pain, swelling, muscle stiffness, or redness at the injection site
- sore throat
- stuffy nose
This is not a complete list of all side effects that may occur. If you have
questions or need medical advice about side effects, contact your doctor or health care
provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at
Some MEDICINES MAY INTERACT with Flebogamma. Tell your health care provider if you are
taking any other medicines, especially any of the following:
Medicines that may harm the kidney (eg, aminoglycoside antibiotics [eg, gentamicin],
amphotericin B, cyclosporine, nonsteroidal anti-inflammatory drugs [NSAIDs] [eg,
ibuprofen], tacrolimus, vancomycin) because the risk of kidney side effects may be
increased. Ask your doctor if you are unsure if any of your medicines might harm the
Hydantoins (eg, phenytoin) because the risk of side effects may be increased
Vaccinations (eg, measles, mumps, and rubella) because effectiveness may be decreased by
This may not be a complete list of all interactions that may occur. Ask your health care
provider if Flebogamma may interact with other medicines that you take. Check with your
health care provider before you start, stop, or change the dose of any medicine.