FM/CFS/ME RESOURCES - Drug Database - Metaxalone

 

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Drug Database - Metaxalone Metaxalone 400 mg. tablet

Generic Name: metaxalone (meh-TAX-ah-lone)

Brand Names: Skelaxin®

Classification: Muscle Relaxant

Issue Date: July 26, 2002

Metaxalone is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Metaxalone is used, along with rest and physical therapy, to treat injuries and other painful muscular conditions.

  • Before Using This Medicine
  • How To Use This Medicine
  • Precautions While on this Medicine
  • Side Effects
  • Overdosage
  • Drug Interactions
  • Divider
    Before Using This Medicine

    Do not take metaxalone if you have acute intermittent porphyria.

    Before taking metaxalone, tell your doctor if you have liver disease. You may need a lower dose or special monitoring during your therapy.

    It is not known whether metaxalone will harm an unborn baby. Do not take metaxalone without first talking to your doctor if you are pregnant.

    It is also not known whether metaxalone passes into breast milk. Do not take metaxalone without first talking to your doctor if you are breast-feeding a baby.

    Metaxalone is not approved for use in children younger than 12 years of age.

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    How To Use This Medicine

    Take metaxalone exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

    Take each dose with a full glass of water.

    Store metaxalone at room temperature away from moisture and heat.

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    Precautions While on this Medicine

    Use caution when driving, operating machinery, or performing other hazardous activities. Metaxalone may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

    Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking metaxalone.

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    Overdosage

    Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a metaxalone overdose are unknown but might include:

    • low blood pressure
    • weakness
    • fainting
    • confusion
    • nausea
    • severe drowsiness
    • decreased breathing
    • unconsciousness

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    Side Effects

    Get emergency medical help if you have any of these signs of an allergic reaction:

    • hives
    • difficulty breathing
    • swelling of your face, lips, tongue, or throat

    If you experience any of the following uncommon but serious side effects, stop taking nefazodone and seek emergency medical attention or contact your doctor immediately:

    • yellow skin or eyes

    Other, less serious side effects may be more likely to occur. Continue to take metaxalone and talk to your doctor if you experience:

    • drowsiness
    • dizziness
    • headache
    • nervousness
    • irritability
    • nausea
    • upset stomach
    • vomiting

    Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

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    Drug Interactions

    Many drugs can increase the effects of metaxalone, which can lead to heavy sedation. Before taking this medication, tell your doctor if you are taking any of the following medicines:

    • brompheniramine (Dimetane®, Bromfed®)
    • chlorpheniramine (Chlor-Trimeton®, Teldrin®)
    • azatadine (Optimine®)
    • clemastine (Tavist®)
    • meperidine (Demerol®)
    • morphine (MSContin®, MSIR®)
    • propoxyphene (Darvon®, Darvocet®)
    • hydrocodone (Lorcet®, Vicodin®)
    • oxycodone (Percocet®, Percodan®)
    • fentanyl (Duragesic®)
    • codeine (Fiorinal®, Fioricet®, Tylenol#3®)
    • phenobarbital (Solfoton®, Luminal®)
    • amobarbital (Amytal®)
    • secobarbital (Seconal®)
    • chlorpromazine (Thorazine®)
    • fluphenazine (Prolixin®)
    • mesoridazine (Serentil®)
    • perphenazine (Trilafon®)
    • prochlorperazine (Compazine®)
    • thioridazine (Mellaril®)
    • trifluoperazine (Stelazine®)
    • doxepin (Sinequan®)
    • imipramine (Tofranil®)
    • nortriptyline (Pamelor®)
    • fluoxetine (Prozac®)
    • paroxetine (Paxil®)
    • sertraline (Zoloft®)
    • phenelzine (Nardil®)
    • tranylcypromine (Parnate®)

    Drugs other than those listed here may also interact with metaxalone. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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