Discuss With Your Doctor
You may have an increased risk of suicidal thoughts or behavior at the start of
treatment with an antidepressant medication, especially if you are under 18 years
old. Talk with your doctor about this risk.
While you are taking Sarafem you will need to be monitored for worsening
symptoms of depression and/ or suicidal thoughts during the first weeks of
treatment, or whenever your dose is changed.
In addition to you watching for changes in your own symptoms, your family or
other caregivers should be alert to changes in your mood or symptoms. Your doctor
will need to check you at regular visits for at least the first 12 weeks
Do not use Sarafem if you are using any of the following drugs:
- pimozide (Orap®)
- thioridazine (Mellaril®)
- isocarboxazid (Marplan®)
- tranylcypromine (Parnate®)
- phenelzine (Nardil®)
- rasagiline (Azilect®)
- selegiline (Eldepryl®, Emsam®)
Serious and sometimes fatal reactions can occur when these medicines are
taken with Sarafem. You must wait at least 14 days after stopping an
MAO inhibitor before you can take Sarafem. You must wait 5 weeks after stopping
Sarafem before you can take thioridazine (Mellaril®) or an MAOI.
Before taking Sarafem, tell your doctor if you are allergic to any drugs, or
if you have:
- Cirrhosis of the liver
- Kidney disease
- Seizures or epilepsy
- Bipolar disorder (manic depression)
- History of drug abuse or suicidal thoughts
If you have any of these conditions, you may not be able to use Sarafem, or
you may need a dosage adjustment or special tests.
SSRI antidepressants may cause serious or life-threatening lung problems in
newborn babies whose mothers take the medication during pregnancy. However,
you may have a relapse of depression if you stop taking your antidepressant
during pregnancy. If you are planning a pregnancy, or if you become pregnant
while taking Sarafem, do not stop taking the medication without first talking
to your doctor.
Sarafem can pass into breast milk and may harm a nursing baby. Do not use
this medication without telling your doctor if you are breast-feeding a baby.