Precautions While on this Medicine
Sinemet may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if
you take it with alcohol or certain medicines. Use Sinemet with caution. Do not drive
or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids,
muscle relaxers) while you are using Sinemet; it may add to their effects. Ask your
pharmacist if you have questions about which medicines may cause drowsiness.
Sinemet may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise,
or fever may increase these effects. To prevent them, sit up or stand slowly, especially
in the morning. Sit or lie down at the first sign of any of these effects.
Tell your doctor or dentist that you take Sinemet before you receive any medical or
dental care, emergency care, or surgery.
Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused
by Sinemet. Symptoms may include:
- stiff muscles
- abnormal thinking
- fast or irregular heartbeat
- and sweating
Contact your doctor at once if you have any of these symptoms.
Diabetes patients - Sinemet may affect your blood sugar. Check blood sugar levels closely.
Ask your doctor before you change the dose of your diabetes medicine. Sinemet may cause
the results of some tests for urine ketones to be wrong. Ask your doctor before you
change your diet or the dose of your diabetes medicine.
Do not suddenly stop taking Sinemet. Some conditions may become worse when Sinemet
is suddenly stopped. Your dose may need to be slowly lowered by your doctor to avoid
side effects. Gradually increase physical activity as your symptoms improve.
A dark color (red, brown, or black) may appear in your saliva, urine, or sweat after
taking Sinemet. This is not harmful.
The effects of Sinemet might start to wear off between doses. Talk with your doctor if
Sinemet stops working well or if your condition worsens.
Sinemet may affect certain lab test results. Make sure your doctors and lab personnel know
you use Sinemet. Lab tests, including complete blood cell counts and liver function
tests, may be performed while you use Sinemet. These tests may be used to monitor
your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Use Sinemet with caution in ELDERLY patients; they may be more sensitive to its effects.
Sinemet should not be used in CHILDREN; safety and effectiveness have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need
to discuss the benefits and risks of using Sinemet while pregnant. It is not known if
Sinemet is found in breast milk. If you are or will be breast-feeding while you are
using Sinemet, check with your doctor. Discuss any possible risks to your baby.